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HPE Accelerates Secure, Scalable AI Innovations with NVIDIA


HPE Accelerates Secure, Scalable AI Innovations with NVIDIA
  • by: Source Logo
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  • March 17, 2026

Hewlett Packard Enterprise (HPE) has announced a significant expansion of the NVIDIA AI Computing by HPE portfolio, introducing new innovations designed to help enterprises deploy, operationalize, and scale artificial intelligence more effectively. Through its deep partnership and co-engineering efforts with NVIDIA, HPE aims to deliver an advanced portfolio of integrated systems that accelerate time to value for AI while addressing critical enterprise requirements for scale, security, and governance.

Quick Intel

  • HPE has expanded its NVIDIA AI Computing portfolio with new AI servers, turnkey systems, and software powered by NVIDIA Blackwell and future Rubin architectures.

  • The new offerings are designed to help enterprises operationalize AI securely and efficiently, moving from experimentation to production-ready outcomes.

  • HPE Private Cloud AI now features network expansion racks for scaling up to 128 GPUs and is available in an air-gapped configuration for secure, isolated deployments.

  • HPE Alletra Storage MP X10000 has become the first NVIDIA-Certified Storage object-based platform, validating its performance and scale for demanding AI workloads.

  • New multi-workload AI solutions have been introduced for specific industries, including retail, medical research, and manufacturing.

  • HPE Services has launched a new agents hub and financing programs to simplify and accelerate enterprise AI adoption.

Expanding Secure and Scalable AI Architectures for the Enterprise

HPE is addressing the enterprise challenge of securely operationalizing AI with a comprehensive refresh of its AI solutions. The company is expanding HPE Private Cloud AI, its turnkey enterprise AI factory co-engineered with NVIDIA, to deliver greater performance, scalability, and flexibility for enterprise inferencing. Industry leaders such as the Ryder Cup, Danfoss, and the Dallas Cowboys are leveraging this platform to accelerate transformative AI initiatives across their organizations.

New network expansion racks now enable HPE Private Cloud AI deployments to scale up to 128 GPUs, allowing customers to run larger, more demanding AI workloads with a consistent operational experience. To meet the demand for secure or sovereign deployments, the large HPE Private Cloud AI system is now available in an air-gapped configuration, ensuring sensitive data is not exposed to external networks.

"The AI race is fundamentally about speed, scale, and trust," said Antonio Neri, president and CEO, HPE. "Our industry leadership across cloud, networking, and AI enables organizations to operationalize AI securely, efficiently, and at an unprecedented scale. Together with NVIDIA, HPE delivers turnkey AI factories and networks that transform AI ambitions into real enterprise value."

"NVIDIA and HPE are setting a new standard for enterprise AI infrastructure," said Jensen Huang, founder and CEO, NVIDIA. "HPE's leadership across private cloud, networking, and secure on-prem systems uniquely positions them to make AI a core enterprise capability. Together, we are building AI factories and AI grids — foundational infrastructure to embed intelligence into every workflow."

Further enhancing security, HPE ProLiant Compute DL380a Gen12 servers and HPE Private Cloud AI systems are being certified for Fortanix Confidential AI. This joint solution leverages NVIDIA Confidential Computing to enable secure on-premises deployments for AI models and processing of sensitive data without exposure. Additionally, CrowdStrike is delivering agentic security for HPE Private Cloud AI, providing AI-powered threat detection and response to protect AI infrastructure, models, and agents.

New AI Solutions for Retail, Medical Research, and Manufacturing

HPE has introduced new NVIDIA co-designed multi-workload solutions to simplify the deployment of AI use cases for autonomous edge intelligence, retail shopping assistance, video search and summarization, and biomedical research. Each of these solutions combines HPE ProLiant Compute servers with NVIDIA accelerated computing, NVIDIA Spectrum-X Ethernet networking, and NVIDIA AI Enterprise software, based on NVIDIA Enterprise Reference Architectures.

To complement these solutions, HPE is adding the new NVIDIA RTX PRO 4500 Blackwell Server Edition GPU to HPE ProLiant servers for edge deployments, small-language models, vector databases, and data analytics workloads. HPE is developing new solutions built on these GPUs, including integrating the NVIDIA Retail Shopping Assistant Blueprint to streamline deployment across the retail sector.

Enhancing AI Data Pipelines with Expanded NVIDIA Integration

As AI infrastructure moves into production, data pipelines have emerged as a critical performance bottleneck. HPE is working closely with NVIDIA to accelerate every stage of the AI data lifecycle, from ingest to inference. HPE continues to evolve the HPE Alletra MP X10000 to centralize intelligent data handling and optimize how AI workloads process data.

HPE is the first vendor to achieve NVIDIA-Certified Storage validation for object-based systems at the Foundation level with the X10000. This certification signifies that NVIDIA has validated and benchmarked the storage layer's performance for loads of up to 128 GPUs, confirming it can efficiently feed data to accelerated computing resources for faster model training and lower latency inference. To further expand the collaboration, HPE will be supporting the new NVIDIA STX rack-scale reference architecture to develop future AI storage solutions.

New HPE services, financing, and ecosystem solutions are also being introduced to simplify AI adoption. HPE Services is offering a new agents hub to ensure structured and scalable enterprise adoption of agentic AI. Within the hub, HPE is developing and validating agents powered by NVIDIA Nemotron models. HPE Financial Services is also making it easier to advance AI projects with a new 90/9 Advantage financing program.

These latest innovations underscore HPE's commitment to providing the foundational infrastructure enterprises need to turn their AI ambitions into real, scalable, and secure business value.

About HPE

HPE is a leader in essential enterprise technology, bringing together the power of AI, cloud, and networking to help organizations achieve more. As pioneers of possibility, our innovation and expertise advance the way people live and work. We empower our customers across industries to optimize operational performance, transform data into foresight, and maximize their impact. Unlock your boldest ambitions with HPE.

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