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  • AI

Proofpoint Unveils First Agentic AI for Human Communications Intelligence


Proofpoint Unveils First Agentic AI for Human Communications Intelligence
  • by: Source Logo
  • |
  • September 15, 2025

Proofpoint, Inc., a leading cybersecurity and compliance company, has launched the industry's first agentic AI solution for Human Communications Intelligence (HCI). This innovative platform transforms digital communications governance (DCG) by shifting from post-incident compliance to real-time, AI-powered risk reasoning, detection, and prevention. Tailored for enterprises in regulated and litigious industries, it empowers organizations to address human behavior before it escalates into compliance, security, or legal issues. Unlike traditional solutions that rely on keyword or pattern flagging, Proofpoint's HCI interprets human intent, capturing and contextualizing communications across more than 80 channels in real time.

Quick Intel

  • Proofpoint debuts first agentic AI solution for Human Communications Intelligence (HCI).
  • Enables real-time risk detection and prevention across 80+ communication channels.
  • Powered by Nuclei technology for intent-driven, transparent risk assessment.
  • Addresses CISO concerns: collaboration tools (Slack, Teams, Zoom) top risk sources.
  • Reduces false positives by up to 90% with explainable AI supervision.
  • Integrates with Insider Threat Management for proactive risk correlation.

Addressing Modern Communication Risks

A recent study of 1,600 global CISOs indicates that over one-third view collaboration tools like Slack, Teams, and Zoom as the top sources of organizational risk, surpassing GenAI chatbots, perimeter devices, cloud storage, and Microsoft 365. Legacy compliance tools, reliant on connectors and archives, lack the AI-driven intelligence needed to address today’s insider threats, financial misconduct, and regulatory scrutiny. Proofpoint’s HCI, powered by its Nuclei technology (acquired earlier this year), autonomously assesses conversations, flags emerging risks, and provides transparent reasoning, transforming human communications into actionable intelligence. “Legacy connectors are merely proxies that pass content downstream, offering little intelligence,” said Harry Labana, SVP & GM of Proofpoint’s DCG business. “Proofpoint has reimagined capture by moving beyond simply collecting messages to interpreting and reasoning in real time. This transforms the world’s largest source of behavioral data—human conversations—into actionable intelligence that empowers compliance, legal, and security teams to prevent risk before it escalates.”

Key Capabilities of Proofpoint’s DCG Portfolio

Proofpoint’s AI-powered DCG portfolio introduces advanced features for real-time governance:

  • Real-Time Communications Intelligence: Proofpoint Capture, powered by Nuclei technology, ingests data from GenAI chatbots, mobile messaging, collaboration apps, social media, email, voice, and files. Purpose-built AI agents interpret communications at scale, integrating with third-party archives and providing transparent reasoning for flagged content, such as misconduct, insider threats, AI misuse, regulatory violations, and toxic culture signals.
  • Explainable AI Supervision: Proofpoint Supervision analyzes 100% of communications with advanced detection of tone, intent, shorthand, emojis, and code snippets across multiple languages. It reduces long-tail noise by up to 90%, enhancing precision and minimizing manual review for scalable, auditable compliance.
  • Integrated Risk Prevention: HCI signals integrate with Proofpoint Insider Threat Management (ITM), correlating communication risks with endpoint user activity. This creates a real-time feedback loop, surfacing motive, means, and modes of risk to prevent violations, breaches, or litigation, while providing auditable oversight for compliance teams.

Availability and Upcoming Events

Proofpoint’s HCI agents, powered by Nuclei technology, are available now. Enhanced LLMs for Proofpoint Supervision are expected in Q4 2025, with Insider Threat Management integration planned for Q1 2026. Proofpoint will showcase this solution at the SIFMA Social Media and Digital Marketing Seminar (September 17), Protect 2025 conference (September 22-24), and Global RegTech Summit USA (September 25). 

This launch positions Proofpoint as a leader in real-time, AI-driven risk management, enabling enterprises to navigate complex communication environments with precision and compliance.

About Proofpoint, Inc.

Proofpoint, Inc. is a leading cybersecurity and compliance company that protects organizations’ greatest assets and biggest risks: their people. With an integrated suite of cloud-based solutions, Proofpoint helps companies worldwide stop targeted threats, safeguard data, and enhance user resilience against cyber-attacks. Trusted by 85% of the Fortune 100, Proofpoint delivers people-centric security and compliance solutions across email, cloud, social media, and the web.

  • ProofpointAgentic AIHuman Communications IntelligenceCybersecurityCompliance
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