Home
News
Tech Grid
Interviews
Anecdotes
Think Stack
Press Releases
Articles
  • Generative AI

DigitalOcean Launches GPU Droplets with AMD Instinct MI350X for Inference


DigitalOcean Launches GPU Droplets with AMD Instinct MI350X for Inference
  • by: Source Logo
  • |
  • February 20, 2026

DigitalOcean, the Agentic Inference Cloud designed for production AI at scale, today announced the availability of high-performance GPU Droplets powered by AMD Instinct MI350X GPUs. This collaboration with AMD enhances DigitalOcean's inference-optimized platform, providing AI-native companies with greater efficiency for demanding workloads while maintaining predictable costs and operational simplicity.

Quick Intel

  • DigitalOcean now offers GPU Droplets powered by AMD Instinct MI350X GPUs in the Atlanta region for optimized inference performance.
  • The MI350X GPUs, built on AMD CDNA 4 architecture, deliver lower latency, higher token throughput, and support for larger models and context windows.
  • Next quarter, DigitalOcean will deploy liquid-cooled AMD Instinct MI355X GPUs to handle even larger datasets and models.
  • Earlier optimizations with AMD Instinct GPUs achieved 2X throughput and 50% cost reduction for Character.AI.
  • Customers like ACE Studio leverage the MI350X for complex inference while controlling costs and improving efficiency.
  • GPU Droplets feature transparent usage-based pricing, simple setup, enterprise SLAs, observability, HIPAA eligibility, and SOC 2 compliance.

Enhanced Inference Performance

The AMD Instinct MI350X GPUs excel in generative AI and high-performance computing, optimizing the compute-bound prefill phase and enabling high-density inference requests per GPU. Paired with DigitalOcean's inference platform, these GPUs reduce latency while increasing throughput, allowing customers to load massive models with extended context windows. This results in faster, more efficient processing for real-time AI applications and production-scale deployments.

Customer Success and Real-World Impact

DigitalOcean's ongoing optimizations with AMD hardware have delivered measurable gains for demanding users. For example, Character.AI achieved double the production request throughput and halved inference costs through targeted AMD Instinct GPU tuning. Similarly, ACE Studio relies on the MI350X architecture to power its AI-driven music workstation, benefiting from enhanced performance and cost efficiency through close collaboration with both DigitalOcean and AMD.

“At ACE Studio, our mission is to build an AI-driven music workstation for the future of music creation,” said Sean Zhao, Co-Founder & CTO. “As we expand our footprint on DigitalOcean, the next-generation AMD Instinct MI350X architecture, supported by close collaboration on inference optimization with AMD and DigitalOcean, provides us a strong foundation to push performance and cost efficiency even further for our customers.”

Commitment to Simplicity and Accessibility

DigitalOcean prioritizes developer-friendly access to advanced AI infrastructure. GPU Droplets can be provisioned in minutes with integrated security, storage, and networking options. Pricing remains transparent and usage-based, with no hidden fees or complex contracts. Enterprise-grade features—including SLAs, observability tools, HIPAA eligibility, and SOC 2 compliance—make the solution suitable for production environments while keeping operations straightforward.

“These results demonstrate that the DigitalOcean Agentic Inference Cloud isn't just about providing raw compute, but about delivering the operational efficiency, inference optimizations, and scale required for demanding AI builders,” said Vinay Kumar, Chief Product and Technology Officer at DigitalOcean. “The availability of the AMD Instinct MI350X GPUs, combined with DigitalOcean’s inference optimized platform offers our customers a boost in performance and the massive memory capacity needed to run the world’s most complex AI workloads while delivering compelling unit economics.”

"Our collaboration with DigitalOcean is rooted in a shared commitment to pairing leadership AI infrastructure with a platform designed to make large-scale AI applications more accessible to the world’s most ambitious developers and enterprises,” said Negin Oliver, Corporate Vice President of Business Development, Data Center GPU Business at AMD. “By bringing the AMD Instinct MI350 Series GPUs to DigitalOcean’s Agentic Inference Cloud, we are empowering startups and enterprises alike to deploy and scale next-generation AI workloads with confidence.”

This expansion builds on prior DigitalOcean-AMD partnerships, including the AMD Developer Cloud and earlier MI300X and MI325X GPU availability. By combining cutting-edge AMD accelerators with DigitalOcean's focus on simplicity and economics, the platform continues to support AI-native enterprises in scaling production inference reliably and affordably.

About DigitalOcean

DigitalOcean is the Agentic Inference Cloud built for AI-native and Digital-native enterprises scaling production workloads. The platform combines production-ready GPU infrastructure with a full-stack cloud to deliver operational simplicity and predictable economics at scale. By integrating inference capabilities with core cloud services, DigitalOcean’s Agentic Inference Cloud enables customers to expand as they grow — driving durable, compounding usage over time. More than 640,000 customers trust DigitalOcean to power their cloud and AI infrastructure.

  • AI InfrastructureGPU CloudGenerative AI
News Disclaimer
  • Share