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  • Enterprise AI

NVIDIA, US Labs, Companies Build National AI Infrastructure


NVIDIA, US Labs, Companies Build National AI Infrastructure
  • by: Source Logo
  • |
  • October 30, 2025

In a significant move to bolster the United States' position in artificial intelligence, NVIDIA has announced a broad collaboration with the U.S. Department of Energy's national labs and a consortium of leading American companies to build a foundational AI infrastructure. This initiative is designed to power the next industrial revolution, accelerating scientific discovery, driving economic growth, and ensuring the nation's technological leadership. The announcements, made at GTC Washington, D.C., encompass new supercomputers for national research, a blueprint for gigawatt-scale AI factories, and massive infrastructure investments from cloud providers and enterprises.

Quick Intel

  • NVIDIA is collaborating with US national labs and industry partners to build a national AI infrastructure.

  • Seven new AI supercomputers are being built for Argonne and Los Alamos National Laboratories.

  • The Solstice system at Argonne, with 100,000 Blackwell GPUs, will be the DOE's largest AI supercomputer.

  • A new AI Factory Research Center in Virginia will serve as a blueprint for gigawatt-scale AI data centers.

  • Major US companies, including CoreWeave, Lambda, and xAI, are making massive new investments in AI infrastructure.

  • Enterprises like Lilly and Mayo Clinic are building private AI factories to accelerate industry-specific research.

Powering National Security and Scientific Discovery

NVIDIA is accelerating scientific research and innovation by providing the AI infrastructure for seven new systems at Argonne National Laboratory and Los Alamos National Laboratory (LANL). The centerpiece is Solstice, a collaboration with Oracle and the DOE that will feature a record-breaking 100,000 NVIDIA Blackwell GPUs, making it the department's largest AI supercomputer for scientific discovery. Argonne will also host the Equinox system and three other powerful NVIDIA-based systems to expand AI-driven computing access for researchers nationwide. Meanwhile, LANL selected the NVIDIA Vera Rubin platform and Quantum-X800 InfiniBand networking for its next-generation Mission and Vision systems, which will advance research in materials science, climate modeling, and national security applications.

Creating a Blueprint for Gigawatt-Scale AI Factories

Beyond specific systems, NVIDIA is laying the groundwork for the future of AI infrastructure build-outs. The company announced an AI Factory Research Center in Virginia, powered by the Vera Rubin platform, which will accelerate breakthroughs in generative AI and scientific computing. This center will serve as the foundation for NVIDIA Omniverse DSX, a comprehensive blueprint for multi-generation, gigawatt-scale AI factories. This initiative involves a vast partner ecosystem, including engineering firms like Bechtel and Jacobs for digital twin-integrated designs, and power and cooling partners like Eaton, Schneider Electric, and Siemens to model and optimize energy efficiency at an unprecedented scale.

A Nationwide Surge in Private AI Infrastructure Investment

The push for national AI capability is being matched by significant investment from leading U.S. companies. System makers like Cisco, Dell Technologies, and HPE are collaborating on secure, scalable AI infrastructure, including a new AI Factory for Government reference design. Cloud providers and model builders are also making substantial commitments. CoreWeave is establishing a federal-focused business, Lambda is building a 100+ megawatt AI factory in Missouri, and xAI is developing a data center in Memphis that will house over half a million NVIDIA GPUs. This wave of investment ensures a diverse and robust ecosystem for AI innovation within the United States.

Enterprise AI Factories Drive Industry-Specific Breakthroughs

U.S. enterprises are also building dedicated AI infrastructure to solve complex challenges in their respective fields. Pharmaceutical leader Lilly is building the industry's most powerful AI factory with an NVIDIA DGX SuperPOD to accelerate drug discovery and design. Similarly, Mayo Clinic has created an AI factory to deliver the computational power needed to advance healthcare applications, leveraging its vast database of patient information and digitized pathology slides to push the boundaries of medical research and personalized care.

“We are at the dawn of the AI industrial revolution that will define the future of every industry and nation,” said Jensen Huang, founder and CEO of NVIDIA. “It is imperative that America lead the race to the future — this is our generation’s Apollo moment.”

This collective effort between government, national labs, and private industry represents a monumental step in establishing the U.S. as the global leader in AI, creating a foundation for a prosperous future powered by American innovation.

About NVIDIA

NVIDIA is the world leader in AI and accelerated computing.

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